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Tag Archives: stimdate

Methylphenidate

methylphenidate_molecule_razidrug

This is Basic Information about Methylphenidate ( Ritalin , Stimdate … ) you can either post a new topic or reply to … Click Ask a question to post a new question to our community . .

Summary


Stimulant

Stimulants excite the nervous system and increase physiological function.

Read more on TripSit Wiki…


Habit-forming

These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.

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Common

Common drugs are those which are well known and widely used among the drug community. This doesn’t necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.


Dose

Dose
Oral
Light20-40mg
Common40-60mg
Strong60-80mg
Heavy80-100mg+
Insufflated
Light5-15mg
Common15-40mg
Strong40-60mg
Heavy60-75mg+

Duration
Oral
Onset30-120 minutes
Duration2 hours
Insufflated
Onset5-15 minutes
Duration1 hours

Aliasesmph
ritalin
concertaStimdate

EffectsIncreased alertness, Euphoria, Increased motivation, Reduced appetite, Flushing of the face, Increased body temperature, Tachycardia (Increased heart rate) Paranoia, Insomnia.

Interactions

Dangerous

  • αMT
  • Tramadol
    • Tramadol and stimulants both increase the risk of seizures.
  • MAOIs
    • MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably. MAO-A inhibitors with amphetamine can lead to hypertensive crises.

Unsafe

  • DOx
    • The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of amphetamine can easily lead to thought loops. Coming down from amphetamines while the DOx is still active can be quite anxiogenic.
  • NBOMes
    • Amphetamines and NBOMes both provide considerable stimulation. When combined they can result in tachycardia, hypertension, vasoconstriction and in extreme cases heart failure. The anxiogenic and focusing effects of stimulants are also not good in combination with psychedelics as they can lead to unpleasant thought loops. NBOMes are known to cause seizures and stimulants can increase this risk.
  • 2C-T-x
    • Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences. In extreme cases, they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure.
  • 5-MeO-xxT
    • The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.
  • DXM
    • Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues.
  • PCP
    • This combination can easily lead to hypermanic states

Caution

  • Mushrooms
    • Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
  • LSD
    • Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
  • DMT
    • Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
  • Mescaline
    • The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops
  • 2C-x
    • The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally uneccessary because of the stimulating effects of psychedelics. Combination of the stimulating effects may be uncomfortable.
  • Cannabis
    • Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences
  • Ketamine
    • No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.
  • MXE
    • Risk of tachycardia, hypertension, and manic states
  • Cocaine
    • This combination of stimulants will increase strain on the heart. It is not generally worth it as cocaine has a mild blocking effect on dopamine releasers like amphetamine
  • Caffeine
    • This combination of stimulants is not generally necessary and may increase strain on the heart, as well as potentially causing anxiety and greater physical discomfort.
  • Alcohol
    • Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol and the stimulant less. Extended release formulations may severely impede sleep, further worsening the hangover.
  • GHB/GBL
    • Stimulants increase respiration rate allowing a higher dose of sedatives. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.
  • Opioids
    • Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.

Low risk & Increased Effects

  • N2O
  • MDMA
    • Amphetamines increase the neurotoxic effects of MDMA

Low risk & Decreased Effects

  • Benzodiazepines
    • Both can dull each other’s effects, so if one wears off before the other it’s possible to overdose due to the lack of counteraction

Low risk & No Synergy

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Study shows ‘brain doping’ is common in amateur sport

brain-doping razidrug

What is brain enhancement?

So called “smart” drugs that can improve mental function have become popular in recent years. A number of substances have been developed that can improve concentration, attention, memory and cognition.

Methylphenidate: Known by the brand names Ritalin and Concerta among others. It is a psychostimulant used to treat attention deficit hyperactivity disorder (ADHD). Prescriptions for these drugs increased by 50% in the six years from 2007.

Modafinil: This medicine is used to treat the sleep disorder narcolepsy. The drug helps people stay awake and improves alertness and the ability to concentrate.

Aking substances to enhance the brain is more popular among amateur athletes than taking drugs to boost the body.

Researchers in Germany found that 15% of recreational triathletes admitted to brain doping, using prescription medicines that increase attention.

Some 13% of competitors reported using physical enhancers like steroids or human growth hormone.

Brain doping is more popular say the scientists, because many of the substances aren’t banned.

 

The research has been published in the journal Plos One.

Previous studies have shown that, among amateur competitors, the use of performance-enhancing substances is widespread.

This new work used the responses of almost 3,000 triathletes taking part in events in Germany, to analyse the broader picture of physical and cognitive doping.

Researchers believe that many so-called “smart drugs” are being widely used to enhance mental functions outside the patients groups they have been designed to help.

They are also concerned that competitors in a variety of sports may be using these substances to gain an edge.

 

Previous studies have shown that, among amateur competitors, the use of performance-enhancing substances is widespread.

This new work used the responses of almost 3,000 triathletes taking part in events in Germany, to analyse the broader picture of physical and cognitive doping.

Researchers believe that many so-called “smart drugs” are being widely used to enhance mental functions outside the patients groups they have been designed to help.

They are also concerned that competitors in a variety of sports may be using these substances to gain an edge.

 

“There is some searching for additional help, we found a strong connection between those taking legal cognitive enhancers and those taking illicit ones,” said Prof Simon.

“There seems to be a certain proportion of our society that is willing to take a bit more of a risk to gain an advantage.”

 

The authors believe that the sporting status of cognitive enhancement may be affecting the attitudes of some of these amateur sports participants.

Athletes are aware that physical doping is forbidden and drug testing is common in triathlon competitions, including amateur ones.

However the use of cognitive substances is not associated with sanctions and therefore abusing them may seem a lesser infringement.

The researchers believe this reflects attitudes in society where the taking of ADHD medicine doesn’t carry the same stigma as using steroids.

The authors say their research leaves many unanswered questions about brain doping.

Prof Simon said: “On the cognitive level, we don’t know enough about these substances. Is there is a hyper performance effect?”

“What we know is that if you are a patient you are going to perform better than before, but if you are already a high-level performer we don’t know if there is an effect. That’s the big question.”

The researchers warn that, regardless of the enhancement, abusing brain doping substances can have damaging impacts in the long run.

 

A question of substance

The authors accept that getting to a precise definition of what constitutes doping is difficult. They tried to be as clear as possible in their questions on the different types of enhancement.

Physical doping: Have you used substances which can only be prescribed by a doctor, are available in a pharmacy, or can be bought on the black market (such as anabolic steroids, erythropoietin, stimulants, growth hormones) to enhance your physical performance during the last 12 months?

Cognitive doping: Have you used substances which can only be prescribed by a doctor, are available in a pharmacy, or can be bought on the black market (such as caffeine tablets, stimulants, cocaine, methylphenidate, modafinil, beta-blockers) to enhance your cognitive performance during the last 12 months?

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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